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SYMPOSIUM
Year : 2012  |  Volume : 53  |  Issue : 4  |  Page : 179-183

Hormones in pregnancy


1 Department of Obstetrics and Gynecology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
2 Air Force Hospital, Nathu Singh Road, Kanpur Cantt, Uttar Pradesh, India

Correspondence Address:
Navneet Magon
Head, Department of Obstetrics and Gynecology, Air Force Hospital, Nathu Singh Road, Kanpur Cantt, U.P
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0300-1652.107549

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The endocrinology of human pregnancy involves endocrine and metabolic changes that result from physiological alterations at the boundary between mother and fetus. Progesterone and oestrogen have a great role along with other hormones. The controversies of use of progestogen and others are discussed in this chapter. Progesterone has been shown to stimulate the secretion of Th2 and reduces the secretion of Th1 cytokines which maintains pregnancy. Supportive care in early pregnancy is associated with a significant beneficial effect on pregnancy outcome. Prophylactic hormonal supplementation can be recommended for all assisted reproduction techniques cycles. Preterm labor can be prevented by the use of progestogen. The route of administration plays an important role in the drug's safety and efficacy profile in different trimesters of pregnancy. Thyroid disorders have a great impact on pregnancy outcome and needs to be monitored and treated accordingly. Method of locating review: Pubmed, scopus


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