Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Users Online: 44


Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Advertise Contacts Login 
Year : 2020  |  Volume : 61  |  Issue : 5  |  Page : 273-275

Parathyroid adenoma with unusual presentations of rib bone and thoracic vertebrae fractures in a premenopausal female in Ibadan, Nigeria

1 Department of Pathology, University College Hospital; Department of Pathology, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria
2 Department of Pathology, University College Hospital, Ibadan, Oyo State, Nigeria
3 Department of Otorhinolaryngology, University College Hospital, Ibadan, Oyo State, Nigeria
4 Department of Otorhinolaryngology, University College Hospital; Department of Otorhinolaryngology, University of Ibadan, Ibadan, Oyo State, Nigeria

Correspondence Address:
Dr. Omolade O Adegoke
Department of Pathology, College of Medicine, University of Ibadan and University College Hospital, Ibadan, Oyo State
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/nmj.NMJ_29_20

Rights and Permissions

Parathyroid adenoma is the most common cause of primary hyperthyroidism which leads to abnormal calcium homeostasis, hypercalcemia, and reduction in bone density. A 37-year-old female referred from a private health facility with a 1-year history of upper back swelling and pain. The pain was worse when sitting down for long periods and with movement and relieved by rest. There was no antecedent history of trauma, but the patient had noticed poor appetite and weight loss. There were no constipation, no abdominal discomfort, and no symptom suggestive of hyperthyroidism or hypothyroidism. General physical examination revealed kyphoscoliosis, and vital signs were within normal limits. Spine X-ray showed features of cervical spondylosis. Computed tomography (CT) scan and magnetic resonance imaging showed pathologic fractures of the right 9th rib, anterior wedge compression, and reduction of T4 vertebrae with other abnormalities at T4–T5, T5–T6, T7–T8, T10–T11, and L4–L5 vertebrae. Bone marrow aspiration and serum electrophoresis were within normal limits. Serum calcium showed hypercalcemia. A CT scan of the neck was done which showed features of a right superior parathyroid adenoma. Blood count, other serum electrolytes, and thyroid function tests were all normal. A parathyroidectomy with right thyroid lobectomy was done. Histopathological examination of the resected parathyroid gland showed a diagnosis of parathyroid adenoma. A high index of suspicion is needed to diagnose this unusual presentation of parathyroid adenoma. Radiological imaging is an important tool for early diagnosis.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded15    
    Comments [Add]    

Recommend this journal