Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Users Online: 1933

 

Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Advertise Contacts Login 
     
ORIGINAL ARTICLE
Year : 2020  |  Volume : 61  |  Issue : 6  |  Page : 345-350

Sociodemographic and clinical characteristics of highly active antiretroviral Treatment-Naïve human immunodeficiency virus-seropositive patients in Uyo, Nigeria: Are the demographics changing?


1 Department of Internal Medicine, University of Uyo Teaching Hospital, University of Uyo, Uyo, Akwa Ibom State, Nigeria
2 Department of Internal Medicine, University of Nigeria Teaching Hospital, University of Nigeria, Enugu State, Nigeria
3 Department of Internal Medicine, University of Calabar Teaching Hospital, University of Calabar, Calabar, Cross River State, Nigeria

Correspondence Address:
Dr. Blessing Chinenye Ubani
University of Uyo Teaching Hospital, University of Uyo, Uyo, Akwa Ibom State
Nigeria
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/nmj.NMJ_153_20

Rights and Permissions

Background: Human immunodeficiency virus (HIV) infection poses a great health and economic burden, especially in developing nations where a high burden of disease has been described. A previous study in Uyo shows that some characteristics associated with a higher prevalence of HIV infection include female gender, exposure to tertiary level of education, and late disease presentation. This study aimed at determining the sociodemographic and the clinical characteristics of highly active antiretroviral treatment-naïve (HAART-naïve) HIV-seropositive patients at Uyo, Nigeria. Materials and Methods: This was a cross-sectional comparative study of 210 respondents, composed of 105 HAART-naïve HIV-seropositive patients (subjects) and an equal number of sex- and age-matched HIV-negative individuals (controls). Data were collected using pretested interviewer-administered questionnaires and hospital records. Anthropometry and blood pressure (BP) were measured for all the respondents, while clinical and immunologic staging were done for subjects. Data obtained were analyzed using SPSS v 20. P ≤ 0.05 was taken as statistically significant. Results: The mean age of the respondents was 34.5 ± 9.2 years, and the male-to-female ratio was 1:2.3, with no difference between the subjects and controls (P = 0.880 for age and P = 0.943 for gender). Mean body mass index and mean diastolic BP were significantly lower in the subjects (P < 0.001 and 0.037, respectively). Female gender, secondary level of educational attainment, and unskilled employment were significantly associated with HIV infection. Majority of the respondents presented in clinical Stage 1 or 2 disease, with CD4 count >350 cells/ml. Conclusion: The burden of HIV infection is higher in females and in those with sociodemographic characteristics suggestive of lower socioeconomic status, however, majority of these appeared to present in early disease.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3539    
    Printed362    
    Emailed0    
    PDF Downloaded19    
    Comments [Add]    

Recommend this journal